Concentrated Chaste Tree fruit extract • Used in Herbal Medicine to help relieve premenstrual symptoms • Used in Herbal Medicine as a hormone normaliser to help stabilise menstrual cycle irregularities • Used in Herbal Medicine to help relieve symptoms associated with menopause, such as hot flushes
Vitex agnus-castus is used in Herbal Medicine to help relieve premenstrual symptoms, as a hormone normaliser to help stabilise menstrual cycle irregularities, and to help relieve symptoms associated with menopause, such as hot flashes. This vegan, dairy-free and gluten-free formulation comes in a convenient capsule format
Non-Medicinal Ingredients: Tapioca syrup, erythritol, cane sugar, palm oil, natural flavors, xylitol, sunflower lecithin, fruit and vegetable blend [apple (Malus domestica) fruit, beet (Beta vulgaris L.) root, cranberry (Vaccinium macrocarpon) fruit, kale (Brassica oleracea sabellica) leaf, carrot (Daucus carota sativus) root, blueberry (Vaccinium angustifolium) fruit], citric acid, fruit and vegetable juice (color), sea salt, and rebaudioside A (from stevia rebaudiana leaf extract).
Recommended Dose: Children (aged 4 years and above) take one soft chew daily or as recommended by your healthcare practitioner. Take with food a few hours before or after taking other medications or natural health products.
Recommended Use: Helps to maintain immune and cognitive function. Helps in the development and maintenance of bones and teeth (especially in childhood, adolescence, and young adulthood). Helps normal growth and to maintain eyesight, hair, and healthy skin. Source of an antioxidant that helps protect cells against damage caused by free radicals. Helps in energy metabolism and maintains the body’s ability to metabolize nutrients. Source of an antioxidant for the maintenance of good health.
Do not use if package is torn or open. Keep in a cool, dry place.
This product is non-GMO and gluten-free.
†As Quatrefolic®. Quatrefolic® is a Registered Trademark of Gnosis S.p.A.
Biotin and vitamin E combination • An antioxidant and factor in the maintenance of good health • Helps the body to metabolize carbohydrates, fats and proteins • Provides 300 mcg of biotin per dose • Includes 5 IU of vitamin E per dose
ST-TN Capsules is a blend of biotin and vitamin E that helps to support optimal health. Biotin is necessary for the activity of five carboxylases which are involved in macronutrient metabolism.1 Biotin supports: 1) fatty acid synthesis in the liver and adipose tissue; 2) fatty acid oxidation; 3) break down amino acids, cholesterol and odd chain fatty acids; 4) leucine metabolism; 5) glucose production in the kidney and liver, glucose-induced insulin release, and fatty acid synthesis in adipocytes.1,2 Cells that are deficient in biotin are also more susceptible to damage caused by oxidative stress.2 Vitamin E is the most significant membrane antioxidant, and helps maintain the structure of nearly all cell membranes.3 It is a potent free radical scavenger that helps to prevent oxidative DNA damage.3 As vitamin E can compete for free radicals faster than polyunsaturated fatty acids in cell membranes, small levels of vitamin E offer a large amount of antioxidant protection.3 The stable vitamin E radical produced is virtually unreactive, and can be recycled back to its original form, demonstrating its essential role in antioxidant defence.3
References 1. Tong, L. Cell Mol Life Sci. 2013; 70(5): 863-891. 2. Zempleni, J., Hassan, YI, Wijeratne, SSK. Expert Rev Endocrinol Metab. 2008; 3(6): 715-724. 3. Combs, GF. (2012). In GF Combs (Ed.) The Vitamins (pp. 181-211). USA: Elsevier.
Echinacea and flavonoid combination • Echinacea angustifolia is traditionally used in Herbal Medicine to help relieve the symptoms of upper respiratory tract infections and to help relieve sore throats • Provides 1000 mg of Echinacea root per daily dose • Includes 480 mg of grapefruit fruit extract (9600 mg Dried Equivalent, standardized to 45% bioflavonoids) per daily dose • 80 mg of green tea leaf and 40 mg of peppermint leaf per daily dose
Citrigen is a source of Echinacea angustifolia, which is traditionally used to help decrease symptoms of upper respiratory tract infections (URTI) and sore throats. Echinacea reduces the release of pro-inflammatory cytokines from immune cells and invading pathogens, including IL-6 and TNF-α, which contribute to symptoms of URTI.1 Adults who consumed 100 mg of Echinacea root extract daily demonstrated significantly decreased pro-inflammatory IL-6 and TNF-α mRNA levels after four weeks of supplementation.2 Echinacea also stimulates the phagocytic activity of immune cells and decreases the survival of bacteria.1,3 Research demonstrates that echinacea can decrease the secretion of mucin, reducing the amount of mucous produced during infections.3 TRPV1 is a pain receptor present in sensory tissues that integrates pain and inflammatory responses.4 Desensitization of this receptor can block the transmission pain, and receptor agonists may therefore exert analgesic effects.4In vitro research demonstrates that Echinacea angustifolia root is 10 times more effective at activating the TRPV1 receptor than capsaicin, a strong ligand for the receptor.4 As echinacea can activate and desensitize this receptor, it helps reduce pain associated with infections, including sore throats.4
Essential oils from ginger and wormwood for relief of digestive disturbances • Traditionally used in Herbal Medicine to help relieve digestive upsets such as flatulence and abdominal bloating • Provides 90 mg each of ginger essential oil and wormwood oil per daily dose • Also includes 190 mg of oregano flowering tops essential oil, 90 mg of clove leaf essential oil and 40 mg of evening primrose seed oil per daily dose
Candicin is a combination of natural oils that are traditionally used to help alleviate digestive disturbances. Gastrointestinal upsets, including flatulence and abdominal bloating, may result from improper gastric or intestinal transit of food.1 Ginger contains oleoresin, which is responsible for its pungent odour.2 Elements in this resin, including shogaols, gingerols, and zingerone, can bind receptors on endocrine cells in the GI tract and pancreas.2 This results in increased gastric and bile secretion, gastric motility, and gastric emptying.2 Pancreatic digestive enzymes are increasingly released, which decreases the transit time through the intestines and helps relieve digestive upsets.2 Ginger also increases the flow of blood to the mucosal layer of the stomach, and inhibits serotonin receptors, which are responsible for mediating nausea.2Wormwood oil contains absinthin, an extremely bitter compound.3 Similar to the pungent ginger, bitter compounds can bind receptors on endocrine cells in the GI tract and pancreas, synergistically enhancing gastric secretion, motility, and pancreatic digestion.2
REFERENCES 1. Houghton, LA, Whorwell, PJ. Neurogastroenterol Motil. 2005; 17: 500_511. 2. Valussi, M. Functional foods with digestion-enhancing properties. International Journal of Food Sciences and Nutrition. 2012; 63(S1): 82-89. 3. Levit, A, Nowak, S, Meyerhof, W, Behrens, M, Peters, M, Niv, MY. FASEB Journal. 2014; 28(3): 1181-1197.
Combination of black walnut and natural plant ingredients that relieve digestive upsets • Traditionally used in Herbal Medicine as a digestive tonic to aid digestion and help relieve dyspepsia • Quassia, black walnut, and pumpkin seeds are traditionally used in Herbal Medicine as a vermifuge • Provides 400 mg of black walnut hull, quassia bark, and yarrow flower per daily dose • Includes 200 mg each of gentian root and pumpkin seed extract, 300 mg of sweet wormwood herb and 100 mg of clove bud per daily dose
Black Walnut Capsules is a blend of herbs that are traditionally used in Herbal Medicine to help alleviate digestive disturbances. Black walnut, quassia, wormwood and gentian root all contain extremely bitter compounds, including tannins, quassin, absinthin, and amarogentin.1-4 These bitters cause nerves on the taste buds to increase the release of saliva and gastric juices that aid in digestion.4 Bitters can also bind receptors on endocrine cells of the gastrointestinal tract and pancreas, which results in the secretion of the peptide hormone cholecystokinin.5 In turn, this releases bile salts and pancreatic digestive enzymes, increasing gastric motility.5 Gentian root and quassia may help relieve dyspepsia by increasing prostaglandin-mediated cytoprotection in the gastric membrane; prostaglandins stimulate the release of mucous and sodium bicarbonate in the stomach.2,6,7 Quassia, black walnut and pumpkin seeds are also traditionally used in Herbal Medicine as a vermifuge (helps in the expulsion of parasitic worms).
REFERENCES 1. Milind, P, Deepa, K. International Research Journal of Pharmacy. 2011; 2(5): 8-17. 2. Ocampo, R, Mora, G. (2011). In M. Rai, D. Acharya, JL. Rios (Eds.), Ethnomedicinal Plants Revitalization of Traditional Knowledge of Herbs (pp. 301-332). Boca Raton, FL: Taylor & Francis Group, LLC. 3. Levit, A, Nowak, S, Meyerhof, W, Behrens, M, Peters, M, Niv, MY. FASEB Journal. 2014; 28(3): 1181-1197. 4. Godstime, O, Felix, E, Augustina, J, Christopher, E. Journal of Pharmaceutical, Chemical and Biological Sciences. 2014; 2(2):77-85. 5. Valussi, M. International Journal of Food Sciences and Nutrition. 2012; 63(S1): 82_89. 6. Niiho, Y, Yamazaki, T, Nakajima, Y, Yamamoto, T, Ando, H, Hirai, Y, Toriizuka, K, Ida, Y. J Nat Med. 2006; 60: 82_88. 7. Wallace, JL. Physiol Rev. 2008; 88: 1547_1565.
Combination of berberine extracts from natural plant sources • Traditionally used in Herbal Medicine as a bitter to aid digestion, to help relieve digestive disturbances such as dyspepsia, and as a mild laxative • Includes goldenseal root extract, barberry root and stem extract, barberry root bark, Oregon grape root extract, and Oregon grape root
Berberis Formula is a blend of barberry, goldenseal and Oregon grape extracts that are traditionally used in Herbal Medicine to help maintain gastrointestinal health. The main bioactive ingredient in these extracts is berberine.1,2 Recent research demonstrates that berberine inhibits bacterial attachment to the gastric mucosa.3 Berberine also mediates the transport of ions and water across intestinal epithelial cells.3 It helps maintain the balance between electrolytes and water, resulting in an anti-diarrheal effect.3 Berberine can increase the expression of the Na+; H+ exchanger and aquaporin,2 which help enhance the absorption of sodium and water, respectively.3,4Berberine also promotes proper intestinal epithelial tight junction formation, and decreases the permeability of these cells to promote appropriate gastrointestinal barrier function.5 During low contractile states, berberine stimulates the jejunum through the activation of muscarinic receptors, resulting in increased intestinal motility, and a mild laxative effect.6
References 1. Javadzadeh, SM, Ebrahimi, A. Sci. Agri. 2013; 1(2): 61-66. 2. Siow, YL, Sarna, L, O, K. Food Research International. 2011; 44: 2409-2417. 3. Chen, C, Yu, Z, Li, Y, Fichna, J, Storr, M. The American Journal of Chinese Medicine. 2014; 42(5): 1053-1070. 4. Zhang, Y, Wang, X, Sha, S, Liang, S, Zhao, L, Liu, L, Chai, N, Wang, H, Wu, K. BFitoterapia. 2012; 83: 1014-1022. 5. Gu, L, Li, N, Gong, J, Li, Q, Zhu, W, Li, J. The Journal of Infectious Diseases. 2011; 203: 1602-1612. 6. Chen, DP, Xiong, YJ, Lv, BC, Liu, FF, Wang, L, Tang, ZY, Lin, Y. Journal of Pharmacy and Pharmacology. 2013; 65(5): 734-744.
Combination of passionflower and other synergistic herbs • Passionflower, hops, and scullcap are traditionally used in Herbal Medicine as a sleep aid • Hops, scullcap and St. John's wort are traditionally used in Herbal Medicine to help relieve nervousness
Combination of oat, passionflower, skullcap and motherwort • Traditionally used in Herbal Medicine to help relieve nervousness and as a sleep aid in cases of restlessness or insomnia due to mental stress • Traditionally used in Herbal Medicine to help relieve the pain associated with menstruation
Combination of yellow dock and other synergistic herbs • Traditionally used in Herbal Medicine as alterative to help remove accumulated waste products and to help relieve dermatological conditions • Traditionally used in Herbal Medicine to help relieve symptoms of upper respiratory tract infections
Goldenseal root extract • Traditionally used in herbal medicine to help alleviate infectious and inflammatory conditions of the digestive tract such as gastritis, helps aid digestion, increase appetite, relieve digestive disturbances such as dyspepsia, and as a mild laxative
Three species of Echinacea – angustifolia, purpurea and pallida • Traditionally used in Herbal Medicine to help relieve cold symptoms, sore throats and the symptoms of upper respiratory tract infections
Milk thistle seed extract • 300 mg dried equivalent per 1 ml (20 drops) • Traditionally used in Herbal Medicine as hepatoprotectant/liver protectant • Used in Herbal medicine to help support liver function and to help relieve digestive disturbances
Highly concentrated cranberry extract plus vitamin C • Helps prevent recurrent urinary tract infections (UTI) in women • Each capsule provides the equivalent of 21.6 g of dried cranberries • Source of antioxidants
Cranberry Plus capsules contain a concentrated cranberry fruit extract that helps to prevent urinary tract infections while improving antioxidant capacity. Approximately 10-20% of women experience one or more incidents of urinary discomfort or UTI each year.1 Cranberries (Vaccinium macrocarpon) are rich in polyphenol antioxidant compounds such as proanthocyanidins, which reduce the adhesiveness of E. coli bacteria to the uroepithelial cells that line the bladder. In both healthy women and those with a history of bladder infection, supplementation with cranberry extract has been shown to significantly reduce the adhesiveness of two E. coli strains obtained from urine samples.2 Regular cranberry supplementation helps to reduce UTI incidence in women at increased risk of UTI infection,3 and may help to improve lower urinary tract symptoms in men.4 Due to their high polyphenol concentration, cranberries have also been shown to reduce oxidative stress in healthy participants and those with metabolic syndrome.5-7
Diindolylmethane (DIM) formulation • Helps to support/promote healthy estrogen metabolism/balance • Helps reduce the severity and duration of symptoms associated with recurrent breast pain (cyclical mastalgia)
Broad-spectrum blend of phytonutrients formulation • Certified organic and GMO-free • Includes nearly 30 fruits, vegetables, grains and grasses that offer polyphenolic antioxidants • Provides 2,000 mg of spirulina per day to help reduce symptoms of allergic rhinitis, such as nasal discharge, sneezing, nasal congestion and itching • Convenient powder that mixes easily into water or juice
Organic Phyto Greens Powder provides naturally occurring phytonutrients and antioxidants in a certified organic and GMO-free formula. This blend contains a wide variety of organic grains and grasses, including oat, barley, rice and millet, along with organic fruits and vegetables, such as wild strawberry, blackberry, cucumber and ginger. In addition to promoting antioxidant activity, this formula provides 2,000 mg of spirulina per day to help reduce symptoms of allergic rhinitis, such as nasal discharge, congestion, sneezing and itching. Available in a convenient powder format, Organic Phyto Greens Powder can be easily mixed into any liquid to create a phytonutrient-rich drink.
Herbal combination to help reduce cough and cold symptoms in kids • Includes a soothing blend of English ivy, marshmallow and European elder extracts • English Ivy is used as an expectorant to help relieve coughs • Marshmallow is used in Herbal Medicine to relieve throat irritation and associated dry cough in adolescents and children ages 6 years and older • European elder is used in Herbal Medicine to help relieve cold and flu symptoms and relieve fever (promotes sweating) in children 3 to 12 years • Delicious natural raspberry flavour
Kids English Ivy is a great-tasting combination of herbs traditionally used to help relieve symptoms associated with coughs and colds. It provides English ivy, which has been demonstrated in clinical trials to help relieve coughs, promote expectoration, and improve respiratory function in children with chronic bronchitis.1-3A mucilaginous herb, marshmallow contains polysaccharides that coat the mucosal lining of the respiratory tract.4Clinical research supports its traditional use in Herbal Medicine as a demulcent to relieve the irritation of the oral and pharyngeal mucosa and associated dry cough.4Kids English Ivy also includes European elder, an herb well-recognized for its high anthocyanin content.5European elder is used in Herbal Medicine to promote sweating (diaphoretic) to help relieve fever, while helping to relieve symptoms of colds and flus (such as coughs, sore throat and catarrh of the upper respiratory tract). Available in a delicious natural raspberry flavour, Kids English Ivy provides soothing relief of cough and cold symptoms in children 3 years and older.